This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives.Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach.Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.
This book provides a comprehensive, practical, and timely guide to neurorehabilitation for patients affected by tumors of the central nervous system. These patients encounter various physical and psychosocial impairments, due to sensory-motor, psychological and cognitive limitations, as well as depression, anxiety and fatigue. These common tumor and treatment consequences reduce quality of life and produce long-term limitation in functioning and disability that may benefit from rehabilitative interventions.In the early stages of the disease, rehabilitation aims at restoring functioning after tumor treatment, while in the advanced stages, rehabilitation becomes an integral part of palliative care, which aims to increase patients' independence, to prevent complications and to improve quality of life.Based on an interdisciplinary approach, the book is structured in two main parts. The first is devoted to the basics of cancer and to the main clinical features of the tumors of the nervous system, as well as to theessentials of therapeutic approaches. The second part is dedicated to rehabilitation issues, providing the tools for health personnel to take in charge persons affected by neuro-oncological disease. This unique volume is a valuable resource for all health professionals (physicians, psychologists, trainees nurses specialized in neuro-oncology, occupational therapists, physiotherapists, speech therapists) involved in the interdisciplinary management of individuals affected by tumors of the central nervous system.